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KMID : 0363219740120040289
Korean Journal of Dermatology
1974 Volume.12 No. 4 p.289 ~ p.299
Hyperlipoproteinemia Type III (Broad beta disease, Floating beta lipoproteins) with Review of Literatures of Primary Hyperlipoproteinemias


Abstract
A stout and obese fourty five year-old Korean man was affected with hyperlipoproteinemia type ¥². His skin lesion showed yellowish papular eruptive xanthomas with erythematous halo Iocated chiefly on the trunk and extensor aspects of the extremities including both palms. In addition to the skin lesion he showed pea-sized cervical lymphnode swellings, slightly tessellated fundi and, on ECG, premature ventricular contraction. Otherwise no specific findings were seen.
The laboratory examinations showed increases of both serum cholesterol and triglycerides, increased fasting blood sugar level and abnormal glucose tolerance curve with turbid color of fasting blood serum which had been kept standing at 4¡É for 24 hours. On the paper electrophoresis "broad beta band" blending with the pre-beta area was noted.
The authors discussed laboratory characteristics, clinical manifestations and differential diagnosis of primary hyperlipoproteinemia on each type with review of the literatures of the disease.
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